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Are 3D mammograms better than standard imaging? A diverse study aims to find out_我的网站

A |     Are 3D mammograms better than standard 2D imaging for catching advanced cancers?A clinical trial is recruiting thousands of volunteers — including a large number of Black women who face disparities in breast cancer death rates — to try to find out.People like Carole Stovall, a psychologist in Washington, D.C., have signed up for the study to help answer the question.“We all need a mammogram anyway, so why not do it with a study that allows the scientists to understand more and move closer to finding better treatments and ways of maybe even preventing it?” Stovall said.The underrepresentation of women and minorities in research is a long-simmering issue affecting health problems including Alzheimer’s disease, stroke and COVID-19. Trials without diversity lead to gaps in understanding of how new treatments work for all people. “Until we get more Black women into clinical trials, we can’t change the science. And we need better science for Black bodies,” said Ricki Fairley, a breast cancer survivor and advocate who is working on the issue.Black women are 40% more likely to die from breast cancer than white women and tend to be diagnosed younger. But it’s not clear whether 3D mammography is better for them, said Dr. Worta McCaskill-Stevens of the National Cancer Institute.“Are there populations for whom this might be important to have early diagnosis?" asked McCaskill-Stevens. "Or is it harmful,” causing too many false alarms or unneeded follow-up tests and treatments?McCaskill-Stevens, who is Black, leads NCI’s efforts to boost access to cancer research in minority and rural communities. She has joined the study herself.The newer 3D technique has been around for a decade, but there’s never been conclusive evidence that it's better than 2D at detecting advanced cancers. The screening technique combines multiple pictures of the breast taken from different angles to create a 3D-like image. Both 3D and 2D mammograms compress the breast and use low doses of radiation.Prior studies suggest that 3D finds more cancers than 2D, but catching more cancers doesn’t necessarily mean more lives saved. Some cancers missed by standard screening may not progress or need treatment. Previous studies did not randomly assign patients to a screening method, the gold standard for research.The notion “that if it’s new, it’s shiny, then it’s better,” isn’t necessarily true, McCaskill-Stevens said. “Until we have the evidence to support that, then we need well-designed randomized trials.”The trial has enrolled nearly 93,000 women so far with a goal of 128,000. The NCI-funded study is now running in Canada, South Korea, Peru, Argentina, Italy and 32 U.S. states. A site in Thailand will soon begin enrolling patients.“We added more international sites to enhance the trial’s diversity, particularly for Hispanic and Asian women,” said Dr. Etta Pisano, who leads the study. Overall, 42% of participants are Hispanic. As recruiting continues, enrolling Black women and other women of color will “absolutely” continue as a priority, Pisano said.Participants are randomly assigned to either 2D or 3D mammograms and are followed for several years. The number of advanced cancers detected by the two methods will be compared.At the U.S. study sites, 21% of study participants are Black women — that's higher than a typical cancer treatment study, in which 9% of participants are Black, McCaskill-Stevens said.The University of North Carolina has signed up more Black women than any other study site. Nearly a quarter of the nearly 3,000 women enrolled at UNC’s two locations are Black.“Women in North Carolina want to take part in something that’s bigger than them,” said Dr. Cherie Kuzmiak, who leads the UNC arm of the study. “They want this active role in helping determine the future of health care for women.”In Washington, D.C., word of mouth has led to successful recruiting. A chance encounter at her hair salon persuaded Stovall to join the research. While waiting for a hair appointment, she met Georgetown University cancer researcher Lucile Adams-Campbell. The two, both Black, started chatting.“She explained how important it was to get women of color into the program,” said Stovall, who jumped at the chance to catch up on her mammograms after the COVID-19 pandemic delayed screening for her and thousands of others.For Stovall, there was a personal reason to join the research. Her sister recently completed treatment for triple negative breast cancer, an aggressive type that affects Black women at higher rates than white women. Women ages 45 to 74 without a personal history of breast cancer are eligible for the study, which launched in 2017. Many women also are providing blood and cheek swab samples for a database that will be mined for insights.“It’s a dream that people had since the beginning of screening that we wouldn’t fit everybody into the same box,” Pisano said. The study's findings could “reduce disparities if we’re successful, assuming people have access to care.”Stovall, 72, had a brief scare when her mammogram, the traditional 2D type, showed something suspicious. A biopsy ruled out cancer.“I was extremely relieved,” Stovall said. “Everybody I know has heard from me about the need for them to go get a mammogram.”___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.。    日报讯（记者方素菊）8月10日，一列满载货物的冀疆班列从石家庄经济技术开发区路桥专用线缓缓驶出，开往乌鲁木齐乌西站。截至当日，冀疆班列累计开行64列，发运6700多个标准集装箱。

B | 立足冀疆两地资源互补、产业错位发展的特点，省新疆商会充分发挥政企联动、资源聚合的桥梁作用，牵头谋划冀疆班列物流产业项目，成功牵线石家庄经济技术开发区与乌鲁木齐经济技术开发区联动共建冀疆物流枢纽基地，打通两地双向互通的物流通道。自2025年11月30日首趟冀疆班列开行以来，这条横贯东西的铁路物流通道高效运行，发展势头强劲。今年4月10日，冀疆班列纳入全国铁路运行图，固定车次X9831，每周定点常态化发车。

C | 5月，冀疆班列北国物流专用线在石家庄内陆港正式启用，形成双场站协同作业格局，全面保障冀疆班列常态化稳定开行。

D | 同月，依托冀疆班列定点开行、时效稳定、运能充足的优势，以及中国邮政完善的网络布局优势，冀疆班列联合邮政打造“冀疆邮列”服务，深耕电商物流、民生保供等领域，进一步丰富了货源结构、拓宽民生服务场景。通过规模化、常态化运输，冀疆班列有效助力制造业拓展西北市场，带动两地商贸、物流、加工产业联动增收。

E | “过去我们的产品运到新疆，都是走传统卡车运输，不仅耗时久，货物运输风险还比较高。

F | ”龙泉剑钉业集团有限公司总经理屈奥说，搭乘冀疆班列后，运输稳定性显著提升，货损风险大幅降低，产品在新疆市场的竞争力进一步增强。

G | 省新疆商会会长、冀疆班列运输有限公司董事长李鑫东介绍，冀疆班列以务实合作赋能产业援疆，推动两地资源互补、互利共赢。依托常态化运行的冀疆班列，先进的农业技术、轻工配套资源持续落地新疆，延伸了当地特色农业产业链条。

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